THE SYNTHESIS OF FLUORINATED BUSULFAN AND PIPOSULFAN ANALOGS, INCLUDING AN UNSYMMETRICAL BIS-SULFONATE

Authors
Citation
U. Lange et A. Senning, THE SYNTHESIS OF FLUORINATED BUSULFAN AND PIPOSULFAN ANALOGS, INCLUDING AN UNSYMMETRICAL BIS-SULFONATE, Acta chemica Scandinavica, 52(1), 1998, pp. 42-44
Citations number
15
Categorie Soggetti
Chemistry,Biology
Journal title
ISSN journal
0904213X
Volume
52
Issue
1
Year of publication
1998
Pages
42 - 44
Database
ISI
SICI code
0904-213X(1998)52:1<42:TSOFBA>2.0.ZU;2-F
Abstract
1,4-Bis(fluoromethylsulfonyloxy)butane, 1,4-bis[3-(fluoromethylsulfony loxy)-propanoyl] piperazine and 1 oromethylsulfonyloxy)-4-(methylsulfo nyloxy)-butane have been prepared as potential cytostatics of the busu lfan type. The rate of hydrolysis of the first-mentioned has been meas ured.