Mr. Delgiudice et al., SYNTHESIS OF 9-AMINO-, 9-AMINOMETHYL-1,2,3,4-TETRAHYDROACRIDINE AND 1,2,3,4,5,6,7,8-OCTAHYDROACRIDINE DERIVATIVES, Journal of heterocyclic chemistry, 34(6), 1997, pp. 1661-1667
This paper describes the synthesis of 9-amino-2- and 4-hydroxy- and 2,
4-dihydroxy-1,2,3,4-tetrahydroacridines 2 and of 9-aminomethyl-1,2,3,4
-tetrahydro- and 1,2,3,4,5,6,7,8-octahydroacridines 3 starting from th
e corresponding 9-carboxamido derivatives. A new synthetical pathway t
o 9-amino-2-hydroxyacridine 9 is also reported.