THE SYNTHESIS AND TRANSFORMATION OF ETHYL -BENZOYL-1-ETHENYL)AMINO-3-DIMETHYLAMINOPROPENOATE - A NEW SYNTHESIS OF 2,3,4-TRISUBSTITUTED PYRROLES

Authors
MALESIC M KRBAVCIC A GOLOBIC A GOLIC L STANOVNIK B
Citation
M. Malesic et al., THE SYNTHESIS AND TRANSFORMATION OF ETHYL -BENZOYL-1-ETHENYL)AMINO-3-DIMETHYLAMINOPROPENOATE - A NEW SYNTHESIS OF 2,3,4-TRISUBSTITUTED PYRROLES, Journal of heterocyclic chemistry, 34(6), 1997, pp. 1757-1762
Citations number
21
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of heterocyclic chemistry → ACNP
ISSN journal
0022152X
Volume
34
Issue
6
Year of publication
1997
Pages
1757 - 1762
Database
ISI
SICI code
0022-152X(1997)34:6<1757:TSATOE>2.0.ZU;2-W
Abstract
The synthesis of ethyl -benzoyl-1-ethenyl)amino-3-dimethylaminopropeno ate (4) from benzoylacetone (1) via 3-dimethylaminomethylenebenzoylace tone (2) and ethyl N-(2-acetyl-2-benzoy1-1-ethenyl)glycinate (3) and i ts transformation into 4-benzoyl-2-ethoxycarbonyl-3-methylpyrrole (9) is described. Cyclization of 4 into 9 represents a new synthesis of po lysubstituted pyrroles.