GESTATIONAL DIABETES-MELLITUS AND GLUCOSE-INTOLERANCE IN A MEXICAN POPULATION

Objective: To determine the prevalence of gestational diabetes mellitu s (GDM), glucose intolerance (GI) and macrosomia in a Latin Mexican po pulation, using the one-step procedure proposed by the World Health Or ganization. Method: Consecutive pregnant women (n = 667) who attended the antenatal clinic and delivered at the hospital were recruited afte r 24 weeks of gestation, mean 34.2 weeks, range 24-40 weeks. After a m inimum of 3 days with a 150-g carbohydrate diet, a glucose load of 75 g was administered and 2 h after, a blood sample for glucose was taken , plasma was separated and immediately processed for glucose, using a glucose-oxidase method. Results: Twenty women were diagnosed with GDM (3%), 87 had GI (13%) and 560 had a normal glucose response (84%). Mac rosomia occurred in two (10%) of GDM, in nine (10.3%) of GI, and in 29 (5.4%) gravidas with a normal response, respectively. Only one of the macrosomic infants whose mother had GI, had neonatal hypoglycemia and hyperbilirubinemia. Conclusion: The overall prevalence of glucose abn ormalities during pregnancy was 16%. GI in this group was associated t o macrosomia at the same rate as GDM. (C) 1997 International Federatio n of Gynecology and Obstetrics.