Objective: To study a possible association between ultrasound screenin
g in early pregnancy and altered cerebral dominance measured by the pr
evalence of non-right handedness among children, particularly boys. Me
thods: Follow-up of 8 to 9 year old children to women who participated
in a randomised controlled trial on ultrasound screening during pregn
ancy in 1985-87. The children were followed up through a questionnaire
sent to their mothers. The dominant hand of the child was assessed by
eleven questions. The dominant foot by one question. Results: No diff
erences were found in non-right handedness between children in the scr
eening and non-screening group. In separate analyses on ultrasound exp
osure and non-right handedness among boys a significant difference was
found (odds ratio 1.33; 95% confidence interval 1.02-1.74). Conclusio
n: This study could not rule out a possible association between non-ri
ght handedness among boys and ultrasound exposure in early fetal life.
The association was, however, confined to analyses comparing exposed
and non-exposed boys and no associations were found when the compariso
ns were performed according to the randomised groups. (C) 1998 Elsevie
r Science Ireland Ltd.