GETTING THROUGH THE GOLGI-COMPLEX

Authors
Citation
Hrb. Pelham, GETTING THROUGH THE GOLGI-COMPLEX, Trends in cell biology, 8(1), 1998, pp. 45-49
Citations number
58
Categorie Soggetti
Cell Biology
Journal title
ISSN journal
09628924
Volume
8
Issue
1
Year of publication
1998
Pages
45 - 49
Database
ISI
SICI code
0962-8924(1998)8:1<45:GTTG>2.0.ZU;2-R
Abstract
Electron micrographs of the Golgi apparatus typically show a series of flat cisternae stacked together, surrounded by numerous vesicles and tubules. Palade and colleagues established in the 1960s that secretory proteins pass through this morphologically complex organelle as they travel from the endoplasmic reticulum to the cell surface. However, th e precise mechanism of transport through the cisternal stack has prove n a controversial issue. Recent advances in identifying the molecules responsible for this traffic suggest that the solution may not be far away.