Background. The goal of this study was to evaluate the safety and effi
cacy of total thyroidectomy performed for benign thyroid disease. Meth
ods. A total of 106 consecutive patients undergoing total thyroidectom
y for benign disease from October 1982 to July 1995 were reviewed. The
33 men and 73 women had an average age of 46 years (range, 16 to 82 y
ears). Indications for total thyroidectomy were a thyroid nodule with
the history of head and neck radiation in 36 patients, bilateral thyro
id nodules in 35, needle biopsy of a follicular neoplasm or frozen sec
tion diagnosis of a possible malignancy in 18, and toxic goiter in 17.
Total thyroidectomy was performed as the primary operation in 98 Pati
ents, and 8 Patients had a completion reoperation for recurrent diseas
e. Results. Pathology findings revealed benign nodular goiter in 49 pa
tients, follicular adenoma in 26, hyperplasia in 19, and Hashimoto's t
hyroiditis in 12. Postoperative hemorrhage requiring operative hemosta
sis occurred in two patients (1.9%). Two patients had unilateral recur
rent laryngeal nerve (RLN) palsy before operation (1.9%). Three patien
ts had unilateral postoperative RLN palsy (2.8%). Two cases resolved i
n 3 and 4 months. The only permanent RLN injury occurred in a patient
reoperated for a compressive goiter. Early postoperative hypocalcemia
(8.0 mg/dl or less) was found in nine patients (8.5%). No patient had
permanent hypoparathyroidism at long-term follow-up evaluation. Conclu
sions. Total thyroidectomy for benign thyroid disease can avoid reoper
ation for nodular goiter and hyperthyroidism and eliminate any subsequ
ent risk of malignant change in radiated thyroid glands. A low complic
ation rate can be achieved with meticulous surgical technique. Total t
hyroidectomy can be performed safely for bilateral benign thyroid dise
ase.