With current treatment modalities, most patients with early stage Hodg
kin's disease (HD) can be cured. Patients destined to relapse, usually
do so within 3 years after treatment completion. Late relapses do occ
ur but disease recurrence beyond 15 years is extremely rare. We report
a patient with clinical stage IIA nodular sclerosis HD, originally tr
eated with radiotherapy alone, who relapsed 24 years after the initial
diagnosis. Our patient's case indicates the possible need for lifelon
g surveillance of patients with Hodgkin's disease.