ADENOSINE-5'-TETRAPHOSPHATE AND GUANOSINE-5'-TETRAPHOSPHATE - NEW SUBSTRATES OF THE CYTOSOLIC EXOPOLYPHOSPHATASE OF THE YEAST SACCHAROMYCES-CEREVISIAE

Authors
KULAKOVSKAYA TV ANDREEVA NA KULAEV IS
Citation
Tv. Kulakovskaya et al., ADENOSINE-5'-TETRAPHOSPHATE AND GUANOSINE-5'-TETRAPHOSPHATE - NEW SUBSTRATES OF THE CYTOSOLIC EXOPOLYPHOSPHATASE OF THE YEAST SACCHAROMYCES-CEREVISIAE, Biochemistry, 62(9), 1997, pp. 1051-1052
Citations number
15
Journal title
Biochemistry → ACNP
ISSN journal
00062979
Volume
62
Issue
9
Year of publication
1997
Pages
1051 - 1052
Database
ISI
SICI code
0006-2979(1997)62:9<1051:AAG-NS>2.0.ZU;2-Q
Abstract
A cytosolic preparation of Saccharomyces cerevisiae is capable of hydr olzing adenosine-5'-tetraphosphate and guanosine-5'-tetraphosphate wit h activities which are 1.5-2 times greater than that with polyP(15). T he apparent K-m values for hydrolysis of adenosine-5'-tetraphosphate a nd guanosine-5'-tetraphosphate are 100 and 80 mu M, respectively. A co mparative study of inhibitors shows that these activities are inherent characteristics of these exopolyphosphatases.