The feasibility of allatostatin direct immunoassays based on capacitan
ce measurements with TiO2 modified electrodes is presented. The low co
nductance and good dielectric properties of the TiO2 substrate insure
good sensitivity. This was proven by a capacitance decrease of about 1
nF cm(-2) for a 3000 times diluted insect serum sample. The simple co
nstruction and the miniaturisation possibility advocate this structure
for direct immunoassay. (C) 1997 Elsevier Science S.A.