Gc. Deribes et al., THE ANNUAL RISK OF TUBERCULOUS INFECTION IN MADAGASCAR - A STUDY RUN FROM 1991 TO 1994, Bulletin de la Societe de pathologie exotique et de ses filiales, 90(5), 1997, pp. 349-352
This article reports the results of a national tuberculin skin lest su
rvey of childhood age group. The survey period was from december 1991
to june 1994. For the calculation of annual risk of tuberculous infect
ion, 1544 schoolchildren, aged 6 to 10 years old without scare related
to BCG, were included. The antigen used was tuberculin PPD Merieux, i
n order to define a mode of positivity this tuberculin was first teste
d with 250 confirmed pulmonary tuberculous patients : the mode was 16
mm. With the hypothesis of a cut-off point of positivity at 14 mm, the
prevalence of tuberculous infection was found al 9,6 % (with a confid
ence interval of 1,6 %);then, the annual risk of tuberculous infection
was calculated at 1,21 % (from 1 % to 1,42 %). With the hypothesis of
a mode at 16 mm the prevalence of tuberculous infection was found at
10,2 % (with a confidence interval of 2,3 %), hen, the annual risk of
tuberculous infection was calculated at 1,29 % (from 0,97 % to 1,59 %)
. Considering separately two age groups, the annual risk was 1,25 % fo
r 6-8 years old children and 1,32 % for 9-10 years old children. In co
nclusion, the authors stress the important constraints in the achievem
ent of such a survey in developping countries. Though the difficulties
that arised, he standardised methodology used in this survey gives re
liable information. These results could be compared with those of futu
re surveys using the same methodological approach.