The presence of 9 common preservatives was investigated in 100 moistur
izers by high-performance liquid chromatography, According to the manu
facturers/suppliers 88 of the 100 moisturizers contained at least one
of the 9 preservatives. This information was erroneous in 9 cases (10.
2%). When the moisturizers were investigated for the presence of the 9
preservatives which should not be present in the moisturizers accordi
ng to the manufacturers/suppliers, at least one of the preservatives w
as detected in 17 moisturizers (17.0%). Parabens were the most common
preservatives. The concentrations of the 9 preservatives did not excee
d the maximum concentrations allowed in cosmetics. When a patient with
suspected allergic contact dermatitis Pests positively to a preservat
ive, the assessment of present clinical relevance requires demonstrati
on of exposure to the sensitizer. This demonstration cannot rely solel
y on information on the packages or from the manufacturers/suppliers b
ut has often to be supplemented bg chemical analysis.