MULTINEVRITIS IN A PATIENT WITH PRIMARY H YPEREOSINOPHILIA

A 72-old-man with a dramatic weight loss, exhibited a mononeuritis mul tiplex of subacute onset, and myalgia. There was hypoesthesia and weak ness on median and ulnar nerves bilaterally and weakness on left femor al nerve. Electrodiagnostical studies showed an axonal pattern of neur opathy. There was a considerable hypereosinophilia on blood count whit hout any aetiologia found on exhaustive explorations. The idiopathic h ypereosinophilic syndrome with a mononeuritis multiplex was suggested. Histological findings were an acute myelino-axonal degeneration with endoneural oedema, without vasculitis nor eosinophil cell on nerve-bio psy Dramatic improvement occured with corticosteroids and immunosuppre ssive treatment.