DETECTION OF GENETIC STRUCTURES AT SHORT DISTANCES IN THE PISA AREA

The genetic structure of the population of the urban and suburban area of the town of Pisa in Tuscany in Central Italy was studied in 1,174 adults residing in 4 zones in each of 3 sampling areas, using the phen otype and gene frequencies of 9 red cell enzymes, The area investigate d has a surface of about 30 km(2). The enzymes were: acid phosphatase (ACP1), adenosine deaminase (ADA). adenylate kinase (AK1), esterase D (ESD), glyoxalase I (GLOI), glutamic-pyruvic transaminase (GPT), 6-pho sphogluconate dehydrogenase (6-PGD), phosphogluco-mutase 1 (PGM1), and phosphoglycollate phosphatase (PGP). For the analysis of the distribu tions of phenotype and gene frequencies, standardised variances, kinsh ip profiles analysis of correspondences and isonymy were used. It was found that in this area genetic differentiation (possibly due to recen t immigration) can be perceived even at short geographic distances, in dicated by the significant regression of kinship on distance, especial ly visible in the ADA and GPT systems.