INDIVIDUAL T-CELLS HOLD UNEXPECTED CLUES TO THE NATURE OF ANERGY AND MEMORY

The primary interest of our laboratory is understanding how the signal s that a T cell receives influence its behavior during an immune respo nse. Recently, we have focused our attention on the examination of T c ell responses at an individual cell level. This article outlines our a pproach, presents our initial findings, and discusses the implications of these findings relative to our current models of T cell activation .