Jp. Lepine et al., DEPRESSION IN THE COMMUNITY - THE FIRST PAN-EUROPEAN STUDY DEPRES (DEPRESSION RESEARCH IN EUROPEAN-SOCIETY), International clinical psychopharmacology, 12(1), 1997, pp. 19-29
DEPRES (Depression Research in European Society) is the first large pa
n-European survey of depression in the community. A total of 13 359 of
the 78 463 adults who participated in screening interviews across six
countries were identified as suffering from depression, a 6-month pre
valence of 17%. Major depression accounted for 6.9% of the cases of de
pression and minor depression for 1.8%. Depressed subjects in both the
se categories perceived that their working or social lives were substa
ntially impaired by depressive symptoms. The remaining 8.3% of depress
ed subjects considered that their functional impairment was not substa
ntial. A significant proportion of sufferers from depression (43%) fai
led to seek treatment for their depressive symptoms. Of those who did
seek help (57%), most consulted a primary care physician, the frequenc
y of consultation increasing with the severity of depression. Sufferer
s fi om major depression imposed the greatest demand on healthcare res
ources, making almost three times as many visits to their GP or family
doctor as non-sufferers (4.4 vs 1.5 visits over 6 months). More than
two-thirds of depressed subjects (69%) were not prescribed any treatme
nt and when drug therapy was prescribed (31%), only 25% of these subje
cts were given antidepressant drugs. The number of days of work lost d
ue to illness increased with the severity of depression. Major depress
ion had most impact on productive work, with sufferers losing four tim
es as many working days over 6 months as non-sufferers. The results of
the DEPRES survey confirm the high prevalence of depression in the co
mmunity and the burden imposed on the individual sufferer in terms of
impaired quality of life and on society in terms of healthcare utiliza
tion and lost productivity.