BENEFIT OF DYNAMIC OVER STATIC INCUBATION IN THE DETECTION OF A LOW-LEVEL HBSAG (CHRONIC CARRIER) BONE DONOR

Background: Hepatitis B infection can be transmitted by organ or tissu e transplantation. Case Report: A 40-year-old man received a bone graf t from a donor who tested negative for HbsAg with a static-mode assay, The same donor, on a subsequent donation, was found to be HbsAg-posit ive with a dynamic mode assay, The archival sample from the initial do nation also tested HbsAg-positive with the dynamic-mode assay, The rec ipient of the bone, who had received HBV vaccine in the past, did not develop clinical or laboratory evidence of HBV infection, Conclusions: This case highlights the importance of sensitive microbiological test protocols in the context of tissue banking.