MITOMYCIN-C DROPS IN THE POSTOPERATIVE PHARMACOLOGICAL MODULATION OF TRABECULECTOMIES

The efficacy of mitomycin C drops, 0.3mg/ml, was evaluated in the trea tment of 16 early trabeculectomy failures resulting from subconjunctiv al fibrosis. Sixteen eyes of 15 patients diagnosed between the second and fourth postoperative weeks were prospectively and systematically r andomized into two groups for further management Intraocular pressure and bleb status were recorded for a minimum of 6 months, Postoperative use of mitomycin C drops allows modulation of early trabeculectomy fa ilures and enables ophthalmologists to restrict the use of this potent ially toxic drug in patients who show evidence of trabeculectomy failu re.