THE ENDOPLASMIC-RETICULUM CA2- A VIEW FROM THE LUMEN( STORE )

Authors
MELDOLESI J POZZAN T
Citation
J. Meldolesi et T. Pozzan, THE ENDOPLASMIC-RETICULUM CA2- A VIEW FROM THE LUMEN( STORE ), Trends in biochemical sciences, 23(1), 1998, pp. 10-14
Citations number
49
Categorie Soggetti
Biology
Journal title
Trends in biochemical sciences → ACNP
ISSN journal
09680004
Volume
23
Issue
1
Year of publication
1998
Pages
10 - 14
Database
ISI
SICI code
0968-0004(1998)23:1<10:TECAVF>2.0.ZU;2-M
Abstract
The endoplasmic reticulum (ER) and its specialized subcompartments suc h as the sarcoplasmic reticulum, is the main dynamic Ca2+ storage comp artment of the cell. Key cellular functions are regulated, either dire ctly or indirectly, by the free Ca2+ concentration in the ER. This art icle discusses the properties of Ca2+ storage in the ER and considers the functions that appear to be regulated by the Ca2+ stores within th e ER, both in and around the ER and at a distance from it.