CHROMATIN REMODELING MACHINES - SIMILAR MOTORS, ULTERIOR MOTIVES

Authors
CAIRNS BR
Citation
Br. Cairns, CHROMATIN REMODELING MACHINES - SIMILAR MOTORS, ULTERIOR MOTIVES, Trends in biochemical sciences, 23(1), 1998, pp. 20-25
Citations number
40
Categorie Soggetti
Biology
Journal title
Trends in biochemical sciences → ACNP
ISSN journal
09680004
Volume
23
Issue
1
Year of publication
1998
Pages
20 - 25
Database
ISI
SICI code
0968-0004(1998)23:1<20:CRM-SM>2.0.ZU;2-2
Abstract
Chromatin is a dynamic material; chromatin structures can repress tran scription and their remodeling accompanies activation. Recent biochemi cal studies in Drosophila have revealed three multi-protein complexes with ATP-dependent chromatin restructuring activities. Although all co ntain the ATPase ISWI, their properties in vitro are markedly differen t, distinct from SWI-SNF and reveal intriguing connections to both tra nscription and chromatin assembly.