A CONVENIENT SYNTHESIS OF SUBSTITUTED 2-PHENYLNAPHTHALENES FROM PHENYLACETONES

Authors
COTELLE P CATTEAU JP
Citation
P. Cotelle et Jp. Catteau, A CONVENIENT SYNTHESIS OF SUBSTITUTED 2-PHENYLNAPHTHALENES FROM PHENYLACETONES, Tetrahedron letters, 38(17), 1997, pp. 2969-2972
Citations number
19
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
38
Issue
17
Year of publication
1997
Pages
2969 - 2972
Database
ISI
SICI code
0040-4039(1997)38:17<2969:ACSOS2>2.0.ZU;2-6
Abstract
Treatment of phenylacetones 1 with boron tribromide gives the 1,3-dime thyl-2-phenylnaphtalenes 2 in good yields by a tandem aldol condensati on-intramolecular Friedel-Crafts cyclization. In the cases of methoxyp henylacetones, a demethylation occurs leading to 1,3-dimethyl-2-hydrox yphenylnaphtols. (C) 1997 Published by Elsevier Science Ltd.