TOXOPLASMA ENCEPHALITIS IN A HIV PATIENT - UNUSUAL INVOLVEMENT OF THECORPUS-CALLOSUM

In patients with acquired immune-deficiency syndrome, the differential diagnosis between primary brain lymphoma and toxoplasma encephalitis is not radiologically always straightforward, especially in the presen ce of a solitary cerebral lesion. In this context, involvement of the corpus callosum is almost exclusively associated with primary brain ly mphoma. We describe here an HIV-infected patient who presented with a single and large cerebral lesion affecting the corpus callosum, sugges tive of primary brain lymphoma on MRI-scan but who nonetheless respond ed clinically and radiologically to an anti-toxoplasma drug trial conf irming the diagnosis of toxoplasma encephalitis. (C) 1997 Elsevier Sci ence B.V.