1-AZA-1',3'-DIAZA-3,3'-SIGMATROPIC REARRANGEMENTS - A CONVENIENT SYNTHESIS OF BENZIMIDAZOLE DERIVATIVES

Authors
CARVALHO MTVL LOBO AM BRANCO PS PRABHAKAR S
Citation
Mtvl. Carvalho et al., 1-AZA-1',3'-DIAZA-3,3'-SIGMATROPIC REARRANGEMENTS - A CONVENIENT SYNTHESIS OF BENZIMIDAZOLE DERIVATIVES, Tetrahedron letters, 38(17), 1997, pp. 3115-3118
Citations number
13
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
38
Issue
17
Year of publication
1997
Pages
3115 - 3118
Database
ISI
SICI code
0040-4039(1997)38:17<3115:1R-ACS>2.0.ZU;2-3
Abstract
1-Aryl-2-acyl-2-cyanohydrazines undergo smooth thermal rearrangements to provide 2-aminoacylbenzimidazoles in excellent yields. A short synt hesis of the highly mutagenic dietary amine, IQ, is reported. (C) 1997 Elsevier Science Ltd.