M. Hilbe et al., A CASE OF CUTANEOUS EPITHELIOTROPIC MALIG NANT-LYMPHOMA (MYCOSIS-FUNGOIDES) IN A HORSE, Berliner und Munchener Tierarztliche Wochenschrift, 110(3), 1997, pp. 86-89
This article describes an eleven year old mare with apathy, fever, enl
arged mandibular lymphnodes, skin lesions on the upper lip and edemato
us, grey-red mucous membranes in the nose. mouth and vulva. Histopatho
logy revealed infiltrates with atypical lymphocytes forming Pautrier's
microabscesses. The neoplastic cells had large, often indented nuclei
. Immunohistology showed Chat some cells were CD3-positive (Pan T-cell
-marker). The diagnosis of cutaneous epitheliotropic malignant lymphom
a (Mycosis fungoides) was made. The etiology in the horse is unknown.