BILIARY-TRACT COMPLICATIONS OF SIDE-TO-SIDE WITHOUT T-TUBE VERSUS END-TO-END WITH OR WITHOUT T-TUBE CHOLEDOCHOCHOLEDOCHOSTOMY IN LIVER-TRANSPLANT RECIPIENTS
Jm. Rabkin et al., BILIARY-TRACT COMPLICATIONS OF SIDE-TO-SIDE WITHOUT T-TUBE VERSUS END-TO-END WITH OR WITHOUT T-TUBE CHOLEDOCHOCHOLEDOCHOSTOMY IN LIVER-TRANSPLANT RECIPIENTS, Transplantation, 65(2), 1998, pp. 193-199
Background, Biliary anastomotic complications remain a major cause of
morbidity in liver transplant recipients, ranging between 10% and 50%
in large clinical series, An end-to-end choledochocholedochostomy with
or without T tube (CDCD EE with T tube and CDCD EE w/o T tube) and a
Roux-en Y choledochojejunostomy have been standard methods for biliary
drainage, Methods. The objectives of this retrospective study were to
: (1) evaluate the incidence of biliary tract complications using a ne
w method of side-to-side choledochocholedochostomy without T tube (CDC
D SS w/o T tube) and (2) compare the results of CDCD SS w/o T tube wit
h those of CDCD EE with T tube and CDCD EE w/o T tube, From September
1991 through June 1996, 279 orthotopic liver transplants were performe
d in 268 patients and followed through December 1996 (minimum of 6 mon
ths' follow-up). A total of 227 CDCD anastomoses in 220 patients were
studied (7 retransplants >30 days): CDCD EE with T tube (n=124), CDCD
EE w/o T tube (n=44), and CDCD SS w/o T tube (n=59). Results. Sixty-ni
ne biliary complications were observed in 220 patients (30%). Anastomo
tic and/or T-tube leaks were seen in 43 patients (19%), and anastomoti
c strictures were found in 26 patients (12%). Forty patients (18%) req
uired percutaneous or endoscopic stent placement (6%) or surgical inte
rventions (12%). CDCD EE with T tube had the highest incidence of bili
ary leak requiring rehospitalization but the lowest anastomotic strict
ure and intervention rate and the lowest B-month mortality rate, Concl
usions, CDCD EE with T tube was superior to CDCD EE or CDCD SS w/o T t
ube despite the increased number of rehospitalizations. CDCD SS w/o T
tube did not offer significant advantages over conventional biliary an
astomotic techniques.