Nb. Atkin et Mc. Baker, DIFFUSE LARGE-CELL (KIEL-1) LYMPHOMA WITH A T(9-11)(P21-22-Q13) AND AMISSING Y AS THE ONLY CHROMOSOME CHANGES, Cancer genetics and cytogenetics, 101(1), 1998, pp. 72-74
We describe a diffuse large cell (Kiel-1) lymphoma in a 76-year-old ma
n that is noteworthy because, apart from a missing Y, the only chromos
ome change was a hitherto undescribed reciprocal translocation, t(9;11
)(p21-22;q13). It is interesting that the breakpoints lay in the vicin
ity of genes that encode proteins engaged in cell cycle control: CCND1
situated at 11q13 and p15 end p16 at 9p21. (C) Elsevier Science Inc.,
1998.