Background. Werner's syndrome associates early aging in young adults,
small height, cataract, glucose intolerance, hypogonadism, skin ulcers
, vascular calcifications and osteoporosis. Case report. We report a n
ew case of Werner's syndrome in a 34-year-old man with suggestive alte
rations of the skin and endocrine anomalies in addition to hypospadias
, urethral stenosis, bilateral mega-ureter and chronic renal failure.
Discussion. The diagnosis of Werner's syndrome in our patient was unqu
estionable because of the clinical presentation and the familial conte
xt. However, the urology anomalies have not been reported in this synd
rome. A simple coincidence cannot be excluded.