PHYSIOLOGICAL AND NUTRITIONAL FACTORS AFFECTING BIOSYNTHESIS OF EXTRACELLULAR PROTEASE BY STREPTOMYCES SPP. G(157)

Authors
SAMPATH P CHANDRAKASAN G
Citation
P. Sampath et G. Chandrakasan, PHYSIOLOGICAL AND NUTRITIONAL FACTORS AFFECTING BIOSYNTHESIS OF EXTRACELLULAR PROTEASE BY STREPTOMYCES SPP. G(157), The New microbiologica, 21(1), 1998, pp. 55-63
Citations number
19
Categorie Soggetti
Microbiology
Journal title
The New microbiologica
ISSN journal
11217138 → ACNP
Volume
21
Issue
1
Year of publication
1998
Pages
55 - 63
Database
ISI
SICI code
1121-7138(1998)21:1<55:PANFAB>2.0.ZU;2-X
Abstract
The aim of the present study was to evaluate the effect of culture con ditions on extracellular protease biosynthesis by Streptomyces spp. G( 157). It was found that there was optimum expression of extracellular proteases in a medium of soya-bean meal (2%), mannitol (2%) at a pH of 7.2 and temperature of 28 degrees C. Among the sugars glucose and sta rch had a greater repressive effect than the others. Phosphate was fou nd to have an inhibitory effect on protease biosynthesis.