REGIOSELECTIVE DIECKMANN CYCLIZATIONS LEADING TO ENANTIOPURE HIGHLY FUNCTIONALIZED TETRAMIC ACID-DERIVATIVES

Authors
ANDREWS MD BREWSTER AG CRAPNELL KM IBBETT AJ JONES T MOLONEY MG PROUT K WATKIN D
Citation
Md. Andrews et al., REGIOSELECTIVE DIECKMANN CYCLIZATIONS LEADING TO ENANTIOPURE HIGHLY FUNCTIONALIZED TETRAMIC ACID-DERIVATIVES, Journal of the Chemical Society. Perkin transactions. I, (2), 1998, pp. 223-235
Citations number
59
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of the Chemical Society. Perkin transactions. I → ACNP
ISSN journal
0300922X
Issue
2
Year of publication
1998
Pages
223 - 235
Database
ISI
SICI code
0300-922X(1998):2<223:RDCLTE>2.0.ZU;2-Z
Abstract
Regioselective Dieckmann cyclisations using an N-acyloxazolidine deriv ed from L-serine give substituted tetramic adds in high yield and enan tioselectivity, The products are easily deprotected under mild conditi ons to give hydroxymethyltetramic acids.