IMAGING NEURONAL NETWORKS IN BEHAVING ANIMALS

Neuronal activity has recently been imaged with single-cell resolution in behaving vertebrates. This was accomplished by using fluorescent c alcium indicators in conjunction with confocal or two-photon microscop y. These optical techniques, along with other new approaches for imagi ng synaptic activity, second messengers, and neurotransmitters and the ir receptors offer great promise for the study of neuronal networks at high resolution in vivo.