COMPILATION OF DNA-SEQUENCES OF ESCHERICHIA-COLI K12 - DESCRIPTION OFTHE INTERACTIVE DATABASES ECD AND ECDC (VERSION 1997)

We have compiled the DNA sequence data for Escherichia coli K12 availa ble from the GenBank and EMBL data libraries and independently from th e literature, We provide the most definitive version of the ECD Escher ichia coli database now exclusively via the World Wide Web System (htt p://susi.bio.uni-giessen.de/ecdc.html). Our database encloses the comp leted genome sequence recently published by two competing groups and a n assembled set of ail elder sequences, The organisation of the databa se allows precise physical location of each individual gene or regulat ory region, even taking into consideration discrepancies in nomenclatu re, The WWW program allows to the user to branch into the original EMB L and SWISS-PROT datafiles, A number of links to other WWW sewers deal ing with E.coli is provided, A FASTA and BLAST search may be performed online. Besides the WWW format a flat file version may be obtained vi a ftp. A number of discrepancies between the two systematic sequence d eterminations and/or the literature have not yet been resolved, Howeve r, our database may serve as a reference source far resolution and/or the assignment of strain difference.