FLYNETS AND GIF-DB, 2 INTERNET DATABASES FOR MOLECULAR-INTERACTIONS IN DROSOPHILA-MELANOGASTER

GIF-DB and FlyNets are two WWW databases describing molecular (protein -DNA, protein-RNA and protein-protein) interactions occuring in the fl y Drosophila melanogaster (http://gifts.univ-mrs.fr/GIFTS_home_page.ht ml). GIF-DB is a specialised database which focuses on molecular inter actions involved in the process of embryonic pattern formation, wherea s FlyNets is a new and more general database, the long-term goal of wh ich is to report on any published molecular interaction occuring in th e fly, The information content of both databases is distributed in spe cific lines arranged into an EMBL- (or GenBank-) like format, These da tabases achieve a high level of integration with other databases such as FlyBase, EMBL, GenBank and SWISS-PROT through numerous hyperlinks. In addition, we also describe SOS-DGDB, a new collection of annotated Drosophila gene sequences, in which binding sites for regulatory prote ins are directly visible on the DNA primary sequence and hyperlinked b oth to GIF-DB and TRANSFAC database entries.