Cortical and subcortical dementias differentially affect cognition wit
h visuospatial sequencing particularly susceptible to damage in subcor
tical dementias. This study examined visuospatial memory and sequencin
g in cortical vs subcortical dementias, Recall of temporal presentatio
n of visuospatial material was examined in Parkinson's disease (PD), A
lzheimer's disease (AD), healthy elderly (HE), and healthy young subje
cts. Predictable pattern vs random sequences assessed ability to utili
ze pattern information to decrease the memory load of the task. Young
subjects performed consistently better than the other groups on random
trials. PD performance was consistent with the healthy older subjects
. AD subjects were worse than the other groups on some trials. These r
esults indicate that while AD subjects have a deficit in temporal orde
ring of visuospatial information relative to HE, PD subjects do not.