ELECTROOCULOGRAPHY IN PIGMENT DISPERSION SYNDROME

Clinical data and the common embryological origin of the pigment epith elium of the iris and retinal pigment epithelium suggest that the latt er may be involved in the pigment dispersion syndrome (PDS), In our st udy functional changes of the retinal pigment epithelium were evaluate d by electro-oculography in 10 PDS patients, 10 patients with chronic open-angle glaucoma (COAG) and 10 normal subjects, The mean dark-troug h latency and Arden ratio for the PDS group were significantly lower t han those of the COAG and control groups, Analysis of the Arden ratios based on the Kruskall-Wallis test revealed that 30% of the PDS values were subnormal with respect to the control group mean -1 SD, These re sults indicate primary involvement of the retinal pigment epithelium i n PDS.