CHARACTERIZATION OF FOX-3, AN AMPC-TYPE PLASMID-MEDIATED BETA-LACTAMASE FROM AN ITALIAN ISOLATE OF KLEBSIELLA-OXYTOCA

Authors
MARCHESE A ARLET G SCHITO GC LAGRANGE PH PHILIPPON A
Citation
A. Marchese et al., CHARACTERIZATION OF FOX-3, AN AMPC-TYPE PLASMID-MEDIATED BETA-LACTAMASE FROM AN ITALIAN ISOLATE OF KLEBSIELLA-OXYTOCA, Antimicrobial agents and chemotherapy, 42(2), 1998, pp. 464-467
Citations number
28
Categorie Soggetti
Pharmacology & Pharmacy",Microbiology
Journal title
Antimicrobial agents and chemotherapy → ACNP
ISSN journal
00664804
Volume
42
Issue
2
Year of publication
1998
Pages
464 - 467
Database
ISI
SICI code
0066-4804(1998)42:2<464:COFAAP>2.0.ZU;2-X
Abstract
Klebsiella oxytoca 1731, which showed a wide spectrum of resistance to beta-lactams, including cefoxitin, was isolated in 1994 from a patien t in Genoa, Italy. This strain contained a plasmid-mediated AmpC beta- lactamase with a pI of 7.25, Sequencing of the corresponding DNA of K. oxytoca 1731 revealed 96 and 97% identities of the deduced amino acid sequence with FOX-1 and FOX-2, respectively.