REGIOSELECTIVE CYCLOPROPANATION REACTIONS USING IODONIUM YLIDES - SYNTHESIS OF PROSTAGLANDIN PRECURSORS

Authors
MORIARTY RM MAY EJ GUO L PRAKASH O
Citation
Rm. Moriarty et al., REGIOSELECTIVE CYCLOPROPANATION REACTIONS USING IODONIUM YLIDES - SYNTHESIS OF PROSTAGLANDIN PRECURSORS, Tetrahedron letters, 39(8), 1998, pp. 765-766
Citations number
17
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
39
Issue
8
Year of publication
1998
Pages
765 - 766
Database
ISI
SICI code
0040-4039(1998)39:8<765:RCRUIY>2.0.ZU;2-L
Abstract
Iodonium ylides of methyl 3-oxo-trans,trans-6,8-tetradecadienoate (1) and diprotected methyl -butyldimethyl-silyloxy)-2,6,8-tetradecatrieneo ate (5) undergo regio-and stereoselective intramolecular cyclopropanat ion with Cu(I)Cl catalysis to form key bicyclo[3.1.0] intermediates fo r prostaglandin synthesis. (C) 1998 Elsevier Science Ltd. All rights r eserved.