PREPARATION OF AROMATIC FARNESOL ANALOGS VIA A CU(I)-MEDIATED GRIGNARD COUPLING OF THP ETHERS

Authors
MECHELKE MF WIEMER DF
Citation
Mf. Mechelke et Df. Wiemer, PREPARATION OF AROMATIC FARNESOL ANALOGS VIA A CU(I)-MEDIATED GRIGNARD COUPLING OF THP ETHERS, Tetrahedron letters, 39(8), 1998, pp. 783-786
Citations number
23
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
39
Issue
8
Year of publication
1998
Pages
783 - 786
Database
ISI
SICI code
0040-4039(1998)39:8<783:POAFAV>2.0.ZU;2-P
Abstract
A Cu(I)-mediated reaction of aromatic Grignard reagents with allylic t etrahydropyranyl ethers results in formation of the coupled products i n good yields. This methodology allows facile synthetic manipulation o f compounds with two reactive allylic positions. (C) 1998 Elsevier Sci ence Ltd. All rights reserved.