LEWIS-ACID-INDUCED REACTION OF HOMOPHTHALIC ANHYDRIDE WITH IMINES - ACONVENIENT SYNTHESIS OF TRANS-ISOQUINOLONIC ACIDS

Authors
YU NF BOUREL L DEPREZ B GESQUIERE JC
Citation
Nf. Yu et al., LEWIS-ACID-INDUCED REACTION OF HOMOPHTHALIC ANHYDRIDE WITH IMINES - ACONVENIENT SYNTHESIS OF TRANS-ISOQUINOLONIC ACIDS, Tetrahedron letters, 39(8), 1998, pp. 829-832
Citations number
13
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
39
Issue
8
Year of publication
1998
Pages
829 - 832
Database
ISI
SICI code
0040-4039(1998)39:8<829:LROHAW>2.0.ZU;2-8
Abstract
Cycloaddition of imines with homophthalic anhydride in the presence of BF3 leads to the trans isomers of isoquinolonic acids with a high ste reoselectivity and avoids the formation of homophtalic amides. This ca talyst extends the scope of the reaction to imines which did not react under previously described conditions. (C) 1998 Elsevier Science Ltd. All rights reserved.