TELOMERASE - A PROMISING MARKER OF BIOLOGICAL IMMORTALITY OF GERM, STEM, AND CANCER-CELLS - A REVIEW

Authors
MEEKER AK COFFEY DS
Citation
Ak. Meeker et Ds. Coffey, TELOMERASE - A PROMISING MARKER OF BIOLOGICAL IMMORTALITY OF GERM, STEM, AND CANCER-CELLS - A REVIEW, Biochemistry, 62(11), 1997, pp. 1323-1331
Citations number
113
Journal title
Biochemistry → ACNP
ISSN journal
00062979
Volume
62
Issue
11
Year of publication
1997
Pages
1323 - 1331
Database
ISI
SICI code
0006-2979(1997)62:11<1323:T-APMO>2.0.ZU;2-V
Abstract
This review will describe the current state of knowledge of telomerase as it relates to human malignancies, focusing primarily on published measurements of this enzymes activity in benign and malignant neoplasm s and their normal tissue counterparts. Key questions concerning the p otential clinical utility of assaying for telomerase activity will be addressed and the implications of recent findings discussed.