Two cases of pemphigus foliaceus in 70-year-old women have been presen
ted. The initial clinical picture, as well as results of histopatholog
ic examinations, suggested the diagnosis of eczema. Because the therap
y was not successful and changes in the clinical picture were observed
, repeated histopathologic and immunofluorescent examinations were car
ried out. Presence of immunologic findings characteristic for pemphigu
s foliaceus formed the basis for verification of the diagnosis and adm
inistration of an appropriate therapy.