A CONVENIENT STEREOSELECTIVE SYNTHESIS OF (1R,2S,3R,4S)-3-(NEOPENTYLOXY)ISOBORNEOL

A convenient preparation of(1 R,2S,3R,4S)-3-(neopentyloxy)isoborneol , 2-dimethylpropoxy)-1,7,7-trimethylbicyclo[2.2.1]; heptan-2-ol; 1a). a valuable chiral auxiliary, is described. The synthesis involves six st eps starting from the readily available camphorquinone (5) and gives 1 a in 48 % overall yield. The key Step is the chemoselective hydrolysis of the less hindered 1,3-dioxolane moiety in the camphorquinone di-ac etal 4.