REGIOSPECIFIC BROMINATION-CYCLIZATION OF SPIROCYCLIC CYCLOHEXANONES AND ITS APPLICATION TO THE SYNTHESIS OF (+ -)-LAURENCIAL/

Authors
MIYASHITA K TANAKA A SHINTAKU H IWATA C
Citation
K. Miyashita et al., REGIOSPECIFIC BROMINATION-CYCLIZATION OF SPIROCYCLIC CYCLOHEXANONES AND ITS APPLICATION TO THE SYNTHESIS OF (+ -)-LAURENCIAL/, Tetrahedron, 54(8), 1998, pp. 1395-1406
Citations number
22
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
54
Issue
8
Year of publication
1998
Pages
1395 - 1406
Database
ISI
SICI code
0040-4020(1998)54:8<1395:RBOSCA>2.0.ZU;2-5
Abstract
Stereospecific bromination-cyclization of spirocyclic cyclohexanones h aving an isopropylidenedioxy group was found to proceed under thermody namically controlled conditions, which was applied to the first synthe sis of (+/-)-laurencial and its epimer. (C) 1998 Elsevier Science Ltd. All rights reserved.