CONJUGATE MICHAEL ADDITIONS WITH MIXED DIORGANOZINCS

Authors
JONES P REDDY CK KNOCHEL P
Citation
P. Jones et al., CONJUGATE MICHAEL ADDITIONS WITH MIXED DIORGANOZINCS, Tetrahedron, 54(8), 1998, pp. 1471-1490
Citations number
42
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
54
Issue
8
Year of publication
1998
Pages
1471 - 1490
Database
ISI
SICI code
0040-4020(1998)54:8<1471:CMAWMD>2.0.ZU;2-G
Abstract
Functionalised mixed alkyl(trimethylsilylmethyl)zinc reagents add effi ciently to a wide variety of Michael accepters in high yield and with exclusive 1,4-regioselectivity, without the need for transition metal catalysis. The trimethylsilylmethyl group behaves as a nontransferable group, and in no cases was transfer of this group observed. (C) 1998 Elsevier Science Ltd. All rights reserved.