Cs. Grange et al., THE USE OF ACUTE HEMODILUTION IN PARTURIENTS UNDERGOING CESAREAN-SECTION, American journal of obstetrics and gynecology, 178(1), 1998, pp. 156-160
OBJECTIVE: Concern over transmissible disease has increased interest i
n methods of minimizing homologous blood transfusion during elective s
urgery. One method is acute hemodilution, a technique previously unrep
orted in parturients. This study was designed to determine its feasibi
lity and safety in women at risk of hemorrhage during cesarean section
. STUDY DESIGN: This technique was performed on 38 parturients. Collec
ted blood was retransfused at the end of surgery or earlier, if requir
ed. Hemoglobin was measured before hemodilution, after hemodilution, b
efore transfusion, after transfusion, and 24 hours postoperatively. Ne
onatal assessment included umbilical blood gases and Apgar scores. RES
ULTS: All patients were hemodynamically stable and no fetal heart rate
abnormalities were observed during the procedure. One patient receive
d homologous blood and 14 received previously donated autologous blood
. Umbilical blood gases were normal and 5-minute Apgar scores were gre
ater than or equal to 7. CONCLUSION: This study suggests that acute he
modilution is well tolerated in parturients undergoing cesarean sectio
n. This may limit exposure to homologous blood transfusion.