PARASITE GLYCOCONJUGATES .4. CHEMICAL SYNTHESIS OF DISACCHARIDE AND PHOSPHORYLATED OLIGOSACCHARIDE FRAGMENTS OF LEISHMANIA-DONOVANI ANTIGENIC LIPOPHOSPHOGLYCAN

Authors
NIKOLAEV AV RUTHERFORD TJ FERGUSON MAJ BRIMACOMBE JS
Citation
Av. Nikolaev et al., PARASITE GLYCOCONJUGATES .4. CHEMICAL SYNTHESIS OF DISACCHARIDE AND PHOSPHORYLATED OLIGOSACCHARIDE FRAGMENTS OF LEISHMANIA-DONOVANI ANTIGENIC LIPOPHOSPHOGLYCAN, Journal of the Chemical Society. Perkin transactions. I, (16), 1995, pp. 1977-1987
Citations number
17
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of the Chemical Society. Perkin transactions. I → ACNP
ISSN journal
0300922X
Issue
16
Year of publication
1995
Pages
1977 - 1987
Database
ISI
SICI code
0300-922X(1995):16<1977:PG.CSO>2.0.ZU;2-0
Abstract
The disaccharide 1, tetraglycosyl monophosphate 2, hexaglycosyl diphos phate 3 and octaglycosyl triphosphate 4, which are fragments of the ph osphoglycan portion of Leishmania donovani lipophosphoglycan, have bee n synthesized. Elongation of the chain was performed using the suitabl y protected glycobiosyl hydrogenphosphonate derivatives 5 and 6 for th e successive introduction of glycobiosyl phosphate units.