Cr. Butlin et al., IGM ANTIPHENOLIC GLYCOLIPID-I ANTIBODY MEASUREMENTS FROM SKIN-SMEAR SITES - CORRELATION WITH VENOUS ANTIBODY-LEVELS AND THE BACTERIAL INDEX, International journal of leprosy and other mycobacterial diseases, 65(4), 1997, pp. 465-468
Measurements of anti-phenolic glycolipid-I antibodies were made in 200
matched samples of capillary blood from the skin-smear site, venous b
lood collected on filter paper, and sera. A close correlation among th
e three samples was observed and a weaker correlation among the antibo
dy levels and the average and skin-smear bacterial index. Capillary bl
ood from the skin-smear site had a consistently higher level of antibo
dies in each sample than did the sera. The collection of capillary blo
od from skin-smear sites is a convenient and economical method of obta
ining samples for serology and for measuring local antibody levels, an
d it may be more sensitive than measurements of antibodies in sera.