Purpose: The authors determine the safety and effectiveness of pericar
dial patch grafts in glaucoma implant surgery. Methods: A retrospectiv
e chart review was conducted on all patients who underwent a glaucoma
implant procedure with the use of a pericardial patch graft to cover t
he subconjunctival portion of the tube at The New York Eye and Ear Inf
irmary between September 1, 1995 and June 30, 1996. Charts were assess
ed for evidence of delle formation, graft rejection, graft-related inf
ection, graft thinning, or tube erosion. Results: Forty-four eyes of 4
4 patients were enrolled. Mean follow-up was 10.2 +/- 4.0 months (rang
e, 2.3 to 18.6 months). Infection, tube erosion, graft rejection, and
graft-related inflammation did not occur. Five eyes were noted to have
asymptomatic thinning of the patch without evidence of tube erosion.
Conclusions: Preserved human cadaveric pericardial patch grafts appear
to be well-tolerated for use with glaucoma drainage devices. As with
other grafting material, potential for graft thinning is possible and
further long-term experience is needed.