Background: Postcholecystectomy pain occurs in 20-30%. The main cause
of this pain remains unclear. Whether the underlying gallbladder disea
se influences the outcome after cholecystectomy is not fully establish
ed. Methods: A multicenter questionnaire study comparing the occurrenc
e of abdominal pain and dyspepsia 5-10 years after cholecystectomy in
345 (222 women, 123 men) patients cholecystectomized for acute cholecy
stitis and in a control group of 296 (213 women, 83 men) patients chol
ecystectomized for uncomplicated symptomatic gallbladder stones. Resul
ts: Of 641 questionnaires, 534 (83%) were completed. Complaints of abd
ominal pain and dyspepsia were found with similar frequencies in the a
cute cholecystitis and gallstone groups. Women had abdominal pain more
often than men (42% versus 29%) (P = 0.01). Although more than one-th
ird complained of abdominal pain after cholecystectomy, 93% had improv
ed or were cured. Conclusion: The outcome after cholecystectomy seems
to be independent of the underlying gallbladder disease (acute cholecy
stitis or elective operations for gallstones).