K. Donath et G. Seifert, TUMOR-SIMULATING SQUAMOUS-CELL METAPLASIA (SCM) IN NECROTIC AREAS OF SALIVARY-GLAND TUMORS, Pathology research and practice, 193(10), 1997, pp. 689-693
Squamous cell metaplasia (SCM) adjacent to necrotic areas of salivary
gland tumours must be distinguished from other types of SCM (focal SCM
in the excretory ducts of salivary glands, necrotizing sialometaplasi
a; focal SCM within salivary gland rumours) in respect to the tissue s
tructure. Based on the high cellular proliferation, arcade-or cord-lik
e pseudoneoplastic SCM develops with stellate extension in the surroun
ding tissue and focal inclusion of goblet cell metaplasia. This prolif
erative SCM resembles the cellular demarcation of radicular dental cys
ts. In the Salivary Gland Register 8 cases of tumour-simulating SCM co
uld be analysed which clinically and morphologically were suspect of s
quamous cell or mucoepidermoid carcinoma. Five cases were localized in
the parotid gland, 2 cases in the submandibular,oland and 1 case in t
he palatinal glands. Tumour-simulating SCM was developed in pleomorphi
c adenomas (5 cases) and in multifocal adenomatous oncocytic hyperplas
ia (3 cases).