CYTOGENETICAL OBSERVATIONS IN A MUCOEPIDERMOID CARCINOMA ARISING FROMHETEROTOPIC INTRANODAL SALIVARY-GLAND TISSUE

Authors
WEDELL B BURIAN P DAHLENFORS R STENMAN G MARK J
Citation
B. Wedell et al., CYTOGENETICAL OBSERVATIONS IN A MUCOEPIDERMOID CARCINOMA ARISING FROMHETEROTOPIC INTRANODAL SALIVARY-GLAND TISSUE, Oncology Reports, 4(3), 1997, pp. 515-516
Citations number
7
Categorie Soggetti
Oncology
Journal title
Oncology Reports → ACNP
ISSN journal
1021335X
Volume
4
Issue
3
Year of publication
1997
Pages
515 - 516
Database
ISI
SICI code
1021-335X(1997)4:3<515:COIAMC>2.0.ZU;2-I
Abstract
The cytogenetical observations in a mucoepidermoid carcinoma (MEG) ari sing from heterotopic intranodal salivary gland tissue are presented. The MEC was characterized by two reciprocal translocations, viz, t(1;7 ) (p36;q11) and t(11;19) (q14-21;p11). The present and the previous st udies show that the last rearrangement or related deviations character ize about 40% of all MEG. The remaining cases form a subgroup distingu ished by trisomies with or without concomitant structural deviations o ther than those affecting 11q14-22. At least MEC of the first subgroup show neither predilection for any specific anatomical site nor for an y age group or particular sex. Inducing agent(s) and genotypic status of the tissue of origin seem to be the decisive factors for the chromo somal patterns in MEG.